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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOP1
All Species:
31.21
Human Site:
S522
Identified Species:
68.67
UniProt:
P52888
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52888
NP_003240.1
689
78840
S522
Q
E
P
L
L
R
M
S
R
H
Y
R
T
G
S
Chimpanzee
Pan troglodytes
XP_001163103
681
78041
S523
V
D
S
L
R
R
L
S
K
H
Y
K
D
G
S
Rhesus Macaque
Macaca mulatta
XP_001117760
648
74185
C487
G
E
V
W
H
V
T
C
A
P
A
E
F
A
M
Dog
Lupus familis
XP_533954
769
86949
S604
K
E
P
L
L
R
M
S
Q
H
Y
R
T
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C1A5
687
78007
S522
K
E
P
L
M
R
M
S
Q
H
Y
R
T
G
S
Rat
Rattus norvegicus
P24155
687
78367
S522
K
E
P
L
M
R
M
S
Q
H
Y
R
T
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424755
698
80358
S540
K
E
P
L
Q
Q
M
S
R
H
Y
K
D
E
S
Frog
Xenopus laevis
NP_001081384
685
78119
S519
R
E
S
L
Q
R
M
S
Q
H
Y
K
S
G
Q
Zebra Danio
Brachydanio rerio
NP_001002355
686
77960
S519
K
E
P
I
Q
R
M
S
K
H
Y
K
T
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25375
712
81915
S551
K
N
E
L
I
N
L
S
S
H
Y
K
T
G
E
Red Bread Mold
Neurospora crassa
Q7SDD5
805
91077
A627
P
S
V
L
A
L
F
A
R
H
Y
E
T
D
N
Conservation
Percent
Protein Identity:
100
61.9
84.6
80.8
N.A.
88.9
88.6
N.A.
N.A.
62.4
71.1
74.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
76.4
86.9
84.6
N.A.
93.4
93.1
N.A.
N.A.
77.7
82.8
85.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
6.6
86.6
N.A.
80
73.3
N.A.
N.A.
60
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
6.6
100
N.A.
100
93.3
N.A.
N.A.
80
80
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.3
23.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.9
41.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
10
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
19
10
0
% D
% Glu:
0
73
10
0
0
0
0
0
0
0
0
19
0
10
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
73
10
% G
% His:
0
0
0
0
10
0
0
0
0
91
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
55
0
0
0
0
0
0
0
19
0
0
46
0
0
0
% K
% Leu:
0
0
0
82
19
10
19
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
19
0
64
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
19
% N
% Pro:
10
0
55
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
28
10
0
0
37
0
0
0
0
0
10
% Q
% Arg:
10
0
0
0
10
64
0
0
28
0
0
37
0
0
0
% R
% Ser:
0
10
19
0
0
0
0
82
10
0
0
0
10
0
46
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
64
0
0
% T
% Val:
10
0
19
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
91
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _